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Caloric Restriction What's Hot

Extending life: Behind the scenes

Calorie-restricted diet delays aging in monkeys

Calorie-restricted diets in people: Mixed results

NIA launches program to identify anti-aging interventions

Caloric Restriction Research Archives

The Basics: Caloric Restriction

What is caloric restriction?

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How does caloric restriction slow down aging?

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Caloric Restriction: Tantalizing Clues to the Aging Process

Dr. Judith Campisi on caloric restriction

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National Institute on Aging launches new program to identify effective anti-aging interventions

Mice in Researcher's Hand
As part of the NIA Interventions
Testing Program, scientists will test
a variety of drugs or other
interventions to see if they extend
life span in laboratory mice.
Photo courtesy of the National
Cancer Institute.
The National Institute on Aging (NIA) is actively engaged in supporting research on the biology of aging. As a means to this end, the NIA is exploring a variety of specific therapies with the potential to extend lifespan and delay disease and dysfunction in mice. Under the umbrella of the NIA Interventions Testing Program, scientists are investigating the safety and feasibility of a variety of interventions.

These interventions include pharmaceuticals, nutraceuticals, foods, diets, dietary supplements, plant extracts, hormones, peptides, amino acids, and other therapies or combinations of therapies. Interventions must be easily obtainable, reasonably priced, and easily delivered in diet or water.

While researchers in universities from across the country are invited to collaborate in this research, the mice will be housed in the University of Michigan’s Geriatrics Center, the Jackson Laboratories, and the University of Texas Health Sciences Center at San Antonio.

Scientists in these centers will help to select five drugs or other interventions each year that will then be tested to see if they extend life span or delay the signs and symptoms of aging in mice. 


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